Blighted means spoiled or ruined by some harmful influence. A blighted crop, blighted lives, a blighted neighbourhood.
The literal sense is agricultural: blight is a disease that kills a crop where it stands, and potato blight caused the Irish famine. The figurative use keeps that sense of something arriving from outside and ruining what was growing.
1adjectiveblightedSpoiled or ruined by some harmful influence.
“The town was blighted by unemployment after the factory closed.”
blighted is a quality of ruin.
From blight + -ed.
Etymology from Wiktionary, CC BY-SA