The bloodstream is the blood as it flows round the body. Enter the bloodstream, in the bloodstream, released into the bloodstream.
The phrase is used for anything carried by the blood — a drug, an infection, a hormone — and a full circuit takes about a minute at rest. A drug injected reaches the bloodstream at once, which is why it acts faster than one swallowed.
1nounbloodstreamThe blood as it flows round the body.
“Alcohol passes from the stomach into the bloodstream and soon reaches the brain.”
bloodstream is a flow.
Blood plus stream, a nineteenth-century compound from medical writing.
From blood + stream.
Etymology from Wiktionary, CC BY-SA